VARI | 2013 Introduction 1 Laboratory Reports Arthur S. Alberts, Ph.D. Cell Structure and Signal Integration 6 William H. Baer II, M.D., Pharm.D. VARI-ClinXus, LLC 8 John F. Bender, Pharm.D. Clinical Operations 10 Patrik Brundin, M.D., Ph.D. Translational Parkinson’s Disease Research 11 Ting-Tung (Anthony) Chang, Ph.D. Small-Animal Imaging Facility/Translational Imaging 14 Nicholas S. Duesbery, Ph.D. Cancer and Developmental Cell Biology 16 Bryn Eagleson, B.S., RLATG Vivarium and Transgenics 19 Table of Contents Kyle A. Furge, Ph.D. Interdisciplinary Renal Oncology 22 Brian B. Haab, Ph.D. Cancer Immunodiagnostics 25 Galen H. Hostetter, M.D. Analytical Pathology 28 Scott D. Jewell, Ph.D. Program for Biospecimen Science 30 Xiaohong Li, Ph.D. Tumor Microenvironment and Metastasis 34 Jeffrey P. MacKeigan, Ph.D. Systems Biology 35 Karsten Melcher, Ph.D. Structural Biology and Biochemistry 38 Cindy K. Miranti, Ph.D. Integrin Signaling and Tumorigenesis 41 Mark W. Neff, Ph.D. Canine Genetics and Genomics 44 Brian J. Nickoloff, M.D., Ph.D. Cutaneous Oncology 46 Giselle S. Sholler, M.D. Neuroblastoma Translational Research 47 Matthew Steensma, M.D. Musculoskeletal Oncology 49 Steven J. Triezenberg, Ph.D. Transcriptional Regulation 51 Jeremy M. Van Raamsdonk, Ph.D. Aging and Neurodegenerative Disease 54 iii
Van Andel Research Institute | ScientificReport Laboratory Reports, continued George F. Vande Woude, Ph.D. Molecular Oncology 57 Craig P. Webb, Ph.D. Translational Medicine 60 Michael Weinreich, Ph.D. Genome Integrity and Tumorigenesis 63 Bart O. Williams, Ph.D. Cell Signaling and Carcinogenesis 66 H. Eric Xu, Ph.D. Structural Sciences 70 Awards for Scientific Achievement 73 Jay Van Andel Award for Outstanding Achievement in Parkinson’s Disease Research Han-Mo Koo Memorial Award Postdoctoral Fellowship Program 76 List of Fellows Student Programs 78 Grand Rapids Area Pre-College Engineering Program Summer Student Internship Program VARI Seminar Series 82 2011 – 2012 Seminars Van Andel Research Institute Organization 85 Boards Office of the Director VAI Administrative Organization iv
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