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2004 Scientific Report

September Rudy

September Rudy Castellani, Michigan State University, East Lansing “Strain variation in sporadic Creutzfeldt-Jakob disease and the role of 14-3-3 protein in diagnosis” Mary Ann Handel, University of Tennessee, Knoxville “Genetic models for analysis of chromosome segregation and gametogenesis” Susan Love, Susan Love Breast Cancer Research Foundation, Santa Barbara, California “The intraductal approach: a window to the breast” October Timothy Willson, GlaxoSmithKline, Research Triangle Park, North Carolina “Molecular mechanisms of nuclear receptor regulation by lipid metabolites” Christopher Leamon, Endocyte, Inc., West Lafayette, Indiana “Folate-targeted technology” Richard Fisher, University of Rochester, New York “Biology and mechanisms of non-Hodgkins lymphoma” November Richard Paules, National Institute of Environmental and Health Sciences, Research Triangle Park, North Carolina “The use of genomics in the quest for predicting the adverse health effects of environmental stressors” Brad Ozanne, Beatson Institute for Cancer Research, Glasgow, Scotland “AP-1 regulates a multigenic invasion program” 85

2004 January Karen Vousden, Beatson Institute for Cancer Research, Glasgow, Scotland “The p53 pathway as a therapeutic target” Patrick Brophy, University of Michigan, Ann Arbor “Ureteric budding: controlling two ends of the event” February Jeffrey Settleman, Harvard Medical School, Boston, Massachusetts “Rho GTPase signaling in development” Josef Prchal, Baylor College of Medicine, Houston, Texas “Tumors, hypoxia, and polycythemic disorders” March Robert Weinberg, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts The Daniel Nathans Lecture: “Mechanisms of human tumor formation” “How cancer begins” (lay audience) Mike Caliguiri, Ohio State University, Columbus “Natural killer cells: biology and clinical implications” Morris Pollard, Walther Cancer Institute, Indianapolis, Indiana “Prevention of hormone-refractory prostate cancer in LW rats” James Basilion, Massachusetts General Hospital, Charlestown, Massachusetts “Noninvasive imaging of gene expression: imaging multiple targets simultaneously” David Frank, Harvard University, Cambridge, Massachusetts “STAT signal transduction in the pathogenesis and treatment of cancer” April Ernst-Robert Lengyel, University of Chicago, Illinois “Regulation of proteolysis by adhesion receptors” Kathleen Siminovitch, Mount Sinai Hospital, Toronto, Canada “The Wiskott Aldrich syndrome protein: forging the link between actin and T cell activation” Jose Cibelli, Michigan State University, East Lansing “Embryonic stem cells by parthenogenesis in mammals” 86

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