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2007 Annual Report

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VAI Bestows Daniel

VAI Bestows Daniel Nathans Memorial Award on Leaders in HPV Research On September 13, Van Andel Institute presented its annual Daniel Nathans Memorial Award to two scientists instrumental in investigating human papillomavirus (HPV) and its links to cervical cancer. Harald zur Hausen, M.D., whose laboratory identified infection by HPV as the main cause of cervical cancer, and Douglas R. Lowy, M.D., whose studies helped lead to highly successful vaccines that prevent infection by these viruses, received the award in a ceremony at the Institute. “The war on cancer began with a promise to develop antiviral vaccines that would prevent malignant disease,” said Van Andel Research Institute Director George F. Vande Woude, Ph.D. “The selection of this year’s awardees is for contributions that allow this promise to be fulfilled.” The Daniel Nathans Memorial Award is conferred by Van Andel Institute’s Board of Scientific Advisors for contributions to biomedical and cancer research. The recipient’s contributions must be far-reaching and significantly benefit public health. The award was established in 2000 to honor the late Dr. Daniel Nathans, a 1978 recipient of the Nobel Prize and a founding member of the Institute’s Board of Scientific Advisors, who died in 1999. (l to r) Harald zur Hausen, M.D., George Vande Woude, Ph.D., and Doug Lowy, M.D. Dr. zur Hausen is Professor Emeritus of the German Cancer Research Center. He studied medicine at the Universities of Bonn, Hamburg and Dusseldorf and received his M.D. in 1960. He is the discoverer or co-discoverer of numerous novel virus types, proposed the role of papillomavirus in the etiology of cervical cancer in the early 1970’s, and proved their role a decade later. Dr. Lowy is Chief, Laboratory of Cellular Oncology, Deputy Director, Division of Basic Sciences & Center for Cancer Research at the National Cancer Institute. He received his M.D. from New York University School of Medicine in 1968. Together with longtime associate John Schiller, Ph.D., his work with virus-like particles (VLP’s) has led to the development of the HPV VLP vaccine. Commercial versions of the vaccine have been approved by the FDA and should have a major impact in cancer prevention. Past recipients of the Daniel Nathans Memorial Award include: Richard D. Klausner, M.D., 2000; Francis S. Collins, M.D., Ph.D., 2001; Lawrence H. Einhorn, M.D., 2002; Robert A. Weinberg, Ph.D., 2003; Brian Druker, M.D., 2004; Tony Hunter, Ph.D., and Tony Pawson, Ph.D., 2005. Van Andel Research Institute

Han-Mo Koo Seminar Series Van Andel Institute hosts speakers from some of the most respected academic, federal, and private research institutes in the nation through its Han-Mo Koo Seminar Series, dedicated to the memory of VAI Principal Investigator Han-Mo Koo (right), who passed away in 2004 following a six-month battle with cancer. Speakers from 2007 (listed in order of speaking schedule): > Moses Lee, Ph.D., Hope College > Raj Kumar, Ph.D., University of Texas Medical Branch > David Kimelman, Ph.D., University of Washington, Seattle > Arthur L. Haas, Ph.D., Louisiana State University Health Sciences Center > S. Stoney Simons Jr., Ph.D., National Institute of Diabetes & Digestive & Kidney Diseases, NIH > John D. Shaughnessy, Jr., Ph.D., University of Arkansas for Medical Science > Melanie H. Cobb, Ph.D., University of Texas Southwestern Medical Center > Christopher G. Wood, M.D., F.A.C.S., University of Texas M.D. Anderson Cancer Center > Jules J. Berman, Ph.D., M.D., National Cancer Institute (former program director) > Shiv Grewal, Ph.D., National Cancer Institute > Ermanno Gherardi, M.D., M.A., Ph.D., MRC Centre > Caroline Alexander, Ph.D., McArdle Laboratory for Cancer Research, University of Wisconsin, Madison > David A. Cheresh, Moores University of California, San Diego Cancer Center > Bruce R. Ksander, Ph.D., Schepens Eye Research Institute; Department of Ophthalmology, Harvard Medical School > Peggy Farnham, Ph.D., University of California, Davis > Daniel D. Von Hoff, M.D., F.A.C.P, Translational Genomics Research Institute > Arul Chinnaiyan, M.D., Ph.D., University of Michigan > Eddy Arnold, Ph.D., Rutgers, The State University of New Jersey > Michael Glotzer, Ph.D., University of Chicago > Andries Zijlstra, Ph.D., Vanderbilt University > Atul Butte, M.D., Ph.D., Stanford University School of Medicine > Michael Ohh, Ph.D., University of Toronto > Phil Hieter, Ph.D., University of British Columbia > Dimiter S. Dimitrov, Ph.D., Sc.D., National Cancer Institute > Robert L. Nussbaum, Ph.D., University of California, San Francisco > Timothy P. Cripe, M.D., Ph.D., Children’s Hospital Medical Center, Cincinnati > Gary D. Stoner, Ph.D., Ohio State University > Stephen Bell, Ph.D., Howard Hughes Medical Institute; Massachusetts Institute of Technology > Diane M. Simeone, M.D., Multidisciplinary Pancreatic Cancer Clinic; U of M Medical School; U of M Comprehensive Cancer Center; U of M Medical Center; U of M Department of Surgery; U of M Medical School > G. David Roodman, M.D., Ph.D., University of Pittsburgh; Center for Bone Biology, University of Pittsburgh Medical Center; University of Pittsburgh Cancer Institute VARIPrestigious Guests 23

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