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2008 Scientific Report

  • Text
  • Report
  • Institute
  • Protein
  • Michigan
  • Signaling
  • Tumor
  • Molecular
  • Laboratory

Cover photo: Prostate

Cover photo: Prostate tumor PC3 cell treated with PI-3K inhibitor. Morphological architecture of a prostate tumor PC3 cell treated with the phosphoinositol-3 kinase inhibitor LY294002 for 72 hours. PC3 cells were immunostained with phallodin (red) and antibody toward vinculin (green). Nuclei were stained with Hoechst (blue). In this cell, inhibition of PI-3K produced the formation of numerous filopodia and microspikes. This is the result of cellular stress, which will eventually lead to the death of the cell. Photo by Laura Lamb of the Miranti lab.

VARI | 2008 Van Andel Research Institute Scientific Report 2008

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