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2009 Scientific Report

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Van Andel Research

Van Andel Research Institute | Scientific Report Recent Publications DeWard, Aaron D., and Arthur S. Alberts. 2009. Ubiquitin-mediated degradation of the formin mDia2 upon completion of cell division. Journal of Biological Chemistry 284(30): 20061–20069. DeWard, Aaron D., Kellie Leali, Richard A. West, George C. Prendergast, and Arthur S. Alberts. 2009. Loss of RhoB expression enhances the myelodysplastic phenotype of mammalian Diaphanous-related formin mDia1 knockout mice. PLoS One 4(9): e7102. Eisenmann, K.M., K.J. Dykema, S.F. Matheson, N.F. Kent, A.D. DeWard, R.A. West, R. Tibes, K.A. Furge, and A.S. Alberts. 2009. 5q– Myelodysplastic syndromes: chromosome 5q genes direct a tumor suppression network sensing actin dynamics. Oncogene 28(39): 3429–3441. Shi, Yongquan, Baoxia Dong, Helen Miliotis, Junye Liu, Arthur S. Alberts, Jinyi Zhang, and Katherine A. Siminovitch. 2009. Src kinase Hck association with the WASp and mDia1 cytoskeletal regulators promotes chemoattractant-induced Hck membrane targeting and activation in neutrophils. Biochemistry and Cell Biology 87(1): 207–216. DeWard, Aaron D., and Arthur S. Alberts. 2008. Microtubule stabilization: formins assert their independence. Current Biology 18(14): R605–R608. Kamasani, Uma, James B. DuHadaway, Arthur S. Alberts, and George C. Prendergast. 2007. mDia function is critical for the cell suicide program triggered by farnesyl transferase inhibition. Cancer Biology & Therapy 6(9): 1422–1427. From left: Matheson, DeWard, West, Kempston, Kitchen, Alberts, Leali, Rodriguez, Lash-Van Wyhe 10

VARI | 2009 Brian Cao, M.D. Laboratory of Antibody Technology Dr. Cao obtained his M.D. from Peking University Medical Center, People’s Republic of China, in 1986. On receiving a CDC fellowship award, he was a visiting scientist at the National Center for Infectious Diseases, Centers for Disease Control and Prevention in Colorado (1991–1994). He next served as a postdoctoral fellow at Harvard (1994–1995) and at Yale (1995–1996). From 1996 to 1999, Dr. Cao was a Scientist Associate in charge of the Monoclonal Antibody Production Laboratory at the Advanced BioScience Laboratories–Basic Research Program at the National Cancer Institute, Frederick Cancer Research and Development Center, Maryland. Dr. Cao joined VARI as a Special Program Investigator in June 1999 and was promoted to Senior Scientific Investigator in July 2006. Staff Students Visiting Scientists Quliang Gu, Ph.D. Ping Zhao, Ph.D. Tessa Grabinski, B.S. Amy Nelson Ximin Chen, M.S. Guipeng Ding, M.S. Hong Lin, M.S. Rui Sun, M.S. Xiaoting Wang, M.S. Victoria Hledin Jessica Karasiewicz Jin Zhu, Ph.D. Yunqian Li, M.S. 11

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